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Radio-deoxynucleoside Analogs used for Imaging tk Expression in a Transgenic Mouse Model of Induced Hepatocellular Carcinoma

Purpose: A group of radiolabeled thymidine analogs were developed as radio-tracers for imaging herpes viral thymidine kinase (HSV1-tk) or its variants used as reporter gene. A transgenic mouse model was created to express tk upon liver injury or naturally occurring hepatocellular carcinoma (HCC). Th...

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Detalhes bibliográficos
Main Authors: Tian, Haibin, Lu, Xincheng, Guo, Hong, Corn, David, Molter, Joseph, Wang, Bingcheng, Luo, Guangbin, Lee, Zhenghong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388592/
https://ncbi.nlm.nih.gov/pubmed/22768027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.3371
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