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In vitro Characterization of Uptake Mechanism of L-[methyl-(3)H]-methionine in Hepatocellular Carcinoma
PURPOSE: Methionine (Met) could be a useful imaging biomarker for the diagnosis of hepatocellular carcinoma (HCC), as demonstrated by PET imaging with L-[methyl-(11)C]-Met. In HCC cells, protein synthesis mainly contributes to radiopharmaceutical uptake. In contrast, lipid synthesis via the phosphat...
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| Publicado no: | Mol Imaging Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698986/ https://ncbi.nlm.nih.gov/pubmed/24488484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0720-9 |
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