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Dimebon Inhibits Calcium-Induced Swelling of Rat Brain Mitochondria But Does Not Alter Calcium Retention or Cytochrome C Release

Dimebon was originally introduced as an antihistamine and subsequently investigated as a possible therapeutic for a variety of disorders, including Alzheimer's disease. One putative mechanism underlying the neuroprotective properties of Dimebon is inhibition of mitochondrial permeability transi...

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Detalhes bibliográficos
Main Authors: Naga, Kranthi Kumari, Geddes, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388507/
https://ncbi.nlm.nih.gov/pubmed/20625939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-010-8130-x
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