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Effects of VM26, a specific inhibitor of type II DNA topoisomerase, on SV40 chromatin replication in vitro.

We have examined the influence of VM26 (teniposide), a specific inhibitor of mammalian type II DNA topoisomerase, on the replication of SV40 minichromosomes in vitro. The replication system we used consists of replicative intermediate SV40 chromatin as substrate which is converted to mature SV40 chr...

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Bibliografiske detaljer
Main Authors: Richter, A, Strausfeld, U
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC338841/
https://ncbi.nlm.nih.gov/pubmed/2848217
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