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The first BCR gene intron contains breakpoints in Philadelphia chromosome positive leukemia.
The hallmark of chronic myelogenous leukemia (CML) is a translocation between chromosomes 9 and 22 - the Philadelphia (Ph') translocation. The translocation is also found in acute lymphocytic leukemia (ALL) albeit in a lower percentage of patients. The breakpoint on chromosome 22 is located wit...
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| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1988
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC338837/ https://ncbi.nlm.nih.gov/pubmed/3194194 |
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