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Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of the BCR gene.

Breakpoints on chromosome 22 in the translocation t(9;22) found in Philadelphia positive acute lymphoblastic leukaemia patients fall within two categories. In the first the breakpoint is localized within the breakpoint cluster region of the BCR gene, analogous to the chromosome 22 breakpoint in chro...

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Detalhes bibliográficos
Main Authors: van der Feltz, M J, Shivji, M K, Allen, P B, Heisterkamp, N, Groffen, J, Wiedemann, L M
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC331530/
https://ncbi.nlm.nih.gov/pubmed/2911461
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