Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.

In chronic myelogenous leukemias (CML) with the t(9;22)(q34;q11) chromosome translocation the breakpoints on chromosome 22 occur within a 5.8-kilobase segment of DNA referred to as "breakpoint cluster region" (bcr). The same cytogenetically indistinguishable translocation occurs in approximately 10%...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Erikson, J, Griffin, C A, ar-Rushdi, A, Valtieri, M, Hoxie, J, Finan, J, Emanuel, B S, Rovera, G, Nowell, P C, Croce, C M
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1986
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3513189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1807
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