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Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome

The majority of the human genome is comprised of non-coding DNA, which frequently contains redundant microsatellite-like trinucleotide repeats. Many of these trinucleotide repeats are involved in triplet repeat expansion diseases (TREDs) such as fragile X syndrome (FXS). After transcription, the tri...

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Autors principals: Kelley, Karen, Chang, Shin-Ju E., Lin, Shi-Lung
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388308/
https://ncbi.nlm.nih.gov/pubmed/22779005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/104796
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