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Staphylococcus aureus Secretes Coagulase and von Willebrand Factor Binding Protein to Modify the Coagulation Cascade and Establish Host Infections

Clinical isolates of Staphylococcus aureus secrete coagulases, polypeptides that bind to and activate prothrombin, thereby converting fibrinogen to fibrin and promoting the clotting of plasma or blood. Two staphylococcal products, the canonical coagulase (Coa) as well as the recently identified von...

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Hlavní autoři: McAdow, Molly, Missiakas, Dominique M., Schneewind, Olaf
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388267/
https://ncbi.nlm.nih.gov/pubmed/22222316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000333447
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