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Staphylococcus aureus Secretes Coagulase and von Willebrand Factor Binding Protein to Modify the Coagulation Cascade and Establish Host Infections

Clinical isolates of Staphylococcus aureus secrete coagulases, polypeptides that bind to and activate prothrombin, thereby converting fibrinogen to fibrin and promoting the clotting of plasma or blood. Two staphylococcal products, the canonical coagulase (Coa) as well as the recently identified von...

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Detalhes bibliográficos
Main Authors: McAdow, Molly, Missiakas, Dominique M., Schneewind, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388267/
https://ncbi.nlm.nih.gov/pubmed/22222316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000333447
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