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Staphylococcus aureus Secretes Coagulase and von Willebrand Factor Binding Protein to Modify the Coagulation Cascade and Establish Host Infections

Clinical isolates of Staphylococcus aureus secrete coagulases, polypeptides that bind to and activate prothrombin, thereby converting fibrinogen to fibrin and promoting the clotting of plasma or blood. Two staphylococcal products, the canonical coagulase (Coa) as well as the recently identified von...

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Autori principali: McAdow, Molly, Missiakas, Dominique M., Schneewind, Olaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388267/
https://ncbi.nlm.nih.gov/pubmed/22222316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000333447
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