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Anti-apoptotic effects of suppressor of cytokine signaling 3 and 1 in psoriasis
Because of their genetically determined capacity to respond to pro-inflammatory stimuli, keratinocytes have a crucial role in the pathogenesis of psoriasis. Upon IFN-γ and TNF-α exposure, psoriatic keratinocytes express exaggerated levels of inflammatory mediators, and show aberrant hyperproliferati...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388239/ https://ncbi.nlm.nih.gov/pubmed/22739986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.69 |
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