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FLT3 in lineage specification and plasticity

FLT3 is a receptor tyrosine kinase that is expressed in CD34(+) hematopoietic stem/progenitor cells (HSPCs) and is important for both normal myeloid and lymphoid differentiation. FLT3 expression in Pax5 negative lymphoid precursors coincides with a window of multilineage differentiation potential in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Greenblatt, Sarah, Small, Donald
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388187/
https://ncbi.nlm.nih.gov/pubmed/22643831
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