Llwytho...

A novel co-operative mechanism linking TGFβ and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells

The advent of a mechanism specific inhibitor imatinib, targeting Bcr-Abl kinase, has paved the way for new treatment strategies in chronic myeloid leukaemia (CML). However, resistance to imatinib is common in patients and has recently been linked to both transforming growth factor-β (TGFβ) and eleva...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Smith, Paul G., Tanaka, Hideo, Chantry, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388181/
https://ncbi.nlm.nih.gov/pubmed/22643838
Tagiau: Ychwanegu Tag
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