Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease

BACKGROUND: Systems biology holds promise as a new approach to drug target identification and drug discovery against neglected tropical diseases. Genome-scale metabolic reconstructions, assembled from annotated genomes and a vast array of bioinformatics/biochemical resources, provide a framework for...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chavali, Arvind K, Blazier, Anna S, Tlaxca, Jose L, Jensen, Paul A, Pearson, Richard D, Papin, Jason A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388006/
https://ncbi.nlm.nih.gov/pubmed/22540944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-27
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