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Reconciling high-throughput gene essentiality data with metabolic network reconstructions
The identification of genes essential for bacterial growth and survival represents a promising strategy for the discovery of antimicrobial targets. Essential genes can be identified on a genome-scale using transposon mutagenesis approaches; however, variability between screens and challenges with in...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478342/ https://ncbi.nlm.nih.gov/pubmed/30973869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006507 |
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