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miR-34 – a microRNA replacement therapy is headed to the clinic

MicroRNA-34 (miR-34) is a master regulator of tumor suppression. It is downregulated in numerous cancers and inhibits malignant growth by repressing genes involved in various oncogenic signaling pathways. Consequently, miR-34 antagonizes processes that are necessary for basic cancer cell viability a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Bader, Andreas G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Research Foundation 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387671/
https://ncbi.nlm.nih.gov/pubmed/22783274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00120
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