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Quit your YAPing: a new target for cancer therapy

The Hippo pathway is an evolutionarily conserved signaling module that plays multiple roles in embryonic development. Components of the pathway, which includes a kinase cascade and a downstream complex composed of YAP and TEAD transcription factors, are dysregulated in a significant fraction of huma...

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Sonraí Bibleagrafaíochta
Príomhúdar: Stanger, Ben Z.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387654/
https://ncbi.nlm.nih.gov/pubmed/22713867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.196501.112
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