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Enhanced Stability of Polymeric Micelles Based on Post-functionalized Poly(ethylene glycol)-b-Poly(γ-propargyl l-glutamate): the Substituent Effect

One of the major obstacles that delay the clinical translation of polymeric micelle drug delivery systems is whether these self-assembled micelles can retain their integrity in blood following intravenous (IV) injection. The objective of this study was to evaluate the impact of core functionalizatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Xiaoyong, Poon, Zhiyong, Engler, Amanda C., Bonner, Daniel K., Hammond, Paula T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387562/
https://ncbi.nlm.nih.gov/pubmed/22376183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm201873u
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