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Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination

Progressive telomere shortening from cell division (replicative aging) provides a barrier for human tumor progression. This program is not conserved in laboratory mice, which have longer telomeres and constitutive telomerase. Wild species that do / do not use replicative aging have been reported, bu...

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Autors principals: Gomes, Nuno M. V., Ryder, Oliver A., Houck, Marlys L., Charter, Suellen J., Walker, William, Forsyth, Nicholas R., Austad, Steven N., Venditt, Chris, Pagel, Mark, Shay, Jerry W, Wright, Woodring E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387546/
https://ncbi.nlm.nih.gov/pubmed/21518243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00718.x
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