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Challenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal models
Experiments with cultures of human tumor cell lines, xenografts of human tumors into immunodeficient mice, and mouse models of human cancer are important tools in the development and testing of anti-cancer drugs. Tumors are complex structures composed of genetically and phenotypically heterogeneous...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387503/ https://ncbi.nlm.nih.gov/pubmed/22446384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.02.031 |
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