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Challenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal models

Experiments with cultures of human tumor cell lines, xenografts of human tumors into immunodeficient mice, and mouse models of human cancer are important tools in the development and testing of anti-cancer drugs. Tumors are complex structures composed of genetically and phenotypically heterogeneous...

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Hlavní autoři: HogenEsch, Harm, Yu Nikitin, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387503/
https://ncbi.nlm.nih.gov/pubmed/22446384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.02.031
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