Vessel-Associated Transforming Growth Factor-Beta1 (TGF-β1) Is Increased in the Bronchial Reticular Basement Membrane in COPD and Normal Smokers

BACKGROUND: Transforming growth factor-beta1 (TGF-β1) is a multipotential cytokine with angiogenic activity. There are only limited data about its role in airway remodeling in COPD. We have previously shown that the reticular basement membrane (Rbm) is hypervascular in the airways of current smokers...

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Main Authors: Soltani, Amir, Sohal, Sukhwinder Singh, Reid, David, Weston, Steve, Wood-Baker, Richard, Walters, E. Haydn
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387255/
https://ncbi.nlm.nih.gov/pubmed/22768115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039736
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