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Cell Invasion by Neisseria meningitidis Requires a Functional Interplay between the Focal Adhesion Kinase, Src and Cortactin

Entry of Neisseria meningitidis (the meningococcus) into human brain microvascular endothelial cells (HBMEC) is mediated by fibronectin or vitronectin bound to the surface protein Opc forming a bridge to the respective integrins. This interaction leads to cytoskeletal rearrangement and uptake of men...

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Bibliografiske detaljer
Main Authors: Slanina, Heiko, Hebling, Sabrina, Hauck, Christoph R., Schubert-Unkmeir, Alexandra
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387252/
https://ncbi.nlm.nih.gov/pubmed/22768099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039613
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