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Relaxation of Adaptive Evolution during the HIV-1 Infection Owing to Reduction of CD4+ T Cell Counts

BACKGROUND: The first stages of HIV-1 infection are essential to establish the diversity of virus population within host. It has been suggested that adaptation to host cells and antibody evasion are the leading forces driving HIV evolution at the initial stages of AIDS infection. In order to gain mo...

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Detalhes bibliográficos
Main Authors: Leal, Élcio, Casseb, Jorge, Hendry, Michael, Busch, Michael P., Diaz, Ricardo Sobhie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387245/
https://ncbi.nlm.nih.gov/pubmed/22768122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039776
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