The Proteasome System in Infection: Impact of β5 and LMP7 on Composition, Maturation and Quantity of Active Proteasome Complexes

Proteasomes are the major enzyme complexes for non-lysosomal protein degradation in eukaryotic cells. Mammals express two sets of catalytic subunits: the constitutive subunits β1, β2 and β5 and the immunosubunits LMP2 (β1i), MECL-1 (β2i) and LMP7 (β5i). The LMP7-propeptide (proLMP7) is required for...

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Bibliografiske detaljer
Main Authors: Joeris, Thorsten, Schmidt, Nicole, Ermert, David, Krienke, Petra, Visekruna, Alexander, Kuckelkorn, Ulrike, Kaufmann, Stefan H. E., Steinhoff, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387237/
https://ncbi.nlm.nih.gov/pubmed/22768135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039827
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