Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

Recent studies have implicated proteasomes in the generation of the antigenic peptides that are presented on major histocompatibility complex class I molecules to T lymphocytes. Interferon gamma modifies the subunit composition of proteasomes and causes changes in their peptidase activities that sho...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Gaczynska, M, Rock, K L, Spies, T, Goldberg, A L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9213
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