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Intramolecular Epistasis and the Evolution of a New Enzymatic Function
Atrazine chlorohydrolase (AtzA) and its close relative melamine deaminase (TriA) differ by just nine amino acid substitutions but have distinct catalytic activities. Together, they offer an informative model system to study the molecular processes that underpin the emergence of new enzymatic functio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387218/ https://ncbi.nlm.nih.gov/pubmed/22768133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039822 |
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