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Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo
The mechanisms by which regulatory T cells (T(regs)) suppress autoantibody production are unclear. Here we have addressed this question using transgenic mice expressing model antigens in the kidney. We report that T(regs) were essential and sufficient to suppress autoreactive B cells in an antigen-s...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387068/ https://ncbi.nlm.nih.gov/pubmed/22689978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201131109 |
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