Y1 and Y5 Receptors Are Both Required for the Regulation of Food Intake and Energy Homeostasis in Mice

Neuropeptide Y (NPY) acting in the hypothalamus is one of the most powerful orexigenic agents known. Of the five known Y receptors, hypothalamic Y1 and Y5 have been most strongly implicated in mediating hyperphagic effects. However, knockout of individual Y1 or Y5 receptors induces late-onset obesit...

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Autors principals: Nguyen, Amy D., Mitchell, Natalie F., Lin, Shu, Macia, Laurence, Yulyaningsih, Ernie, Baldock, Paul A., Enriquez, Ronaldo F., Zhang, Lei, Shi, Yan-Chuan, Zolotukhin, Serge, Herzog, Herbert, Sainsbury, Amanda
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387009/
https://ncbi.nlm.nih.gov/pubmed/22768253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040191
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