TBX5 drives Scn5a expression to regulate cardiac conduction system function

Cardiac conduction system (CCS) disease, which results in disrupted conduction and impaired cardiac rhythm, is common with significant morbidity and mortality. Current treatment options are limited, and rational efforts to develop cell-based and regenerative therapies require knowledge of the molecu...

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Main Authors: Arnolds, David E., Liu, Fang, Fahrenbach, John P., Kim, Gene H., Schillinger, Kurt J., Smemo, Scott, McNally, Elizabeth M., Nobrega, Marcelo A., Patel, Vickas V., Moskowitz, Ivan P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386825/
https://ncbi.nlm.nih.gov/pubmed/22728936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62617
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