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Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia

An emerging theory of schizophrenia postulates that hypofunction of adenosine signaling may contribute to its pathophysiology. This study was designed to test the “adenosine hypothesis” of schizophrenia and to evaluate focal adenosine-based strategies for therapy. We found that augmentation of adeno...

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Detalhes bibliográficos
Main Authors: Shen, Hai-Ying, Singer, Philipp, Lytle, Nikki, Wei, Catherine J., Lan, Jing-Quan, Williams-Karnesky, Rebecca L., Chen, Jiang-Fan, Yee, Benjamin K., Boison, Detlev
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386823/
https://ncbi.nlm.nih.gov/pubmed/22706302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62378
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