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Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells

Natural killer (NK) cells are primary effectors of innate immunity directed against transformed tumor cells. In response, tumor cells have developed mechanisms to evade NK cell–mediated lysis through molecular mechanisms that are not well understood. In the present study, we used a lentiviral shRNA...

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Detalhes bibliográficos
Main Authors: Bellucci, Roberto, Nguyen, Hong-Nam, Martin, Allison, Heinrichs, Stefan, Schinzel, Anna C., Hahn, William C., Ritz, Jerome
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386806/
https://ncbi.nlm.nih.gov/pubmed/22684105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58457
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