TNF Is Necessary for Castration-Induced Prostate Regression, Whereas TRAIL and FasL Are Dispensable

TNF, a proinflammatory and immune-regulatory cytokine, is a potent apoptotic stimulus in vitro. However, there have been few examples of a physiologic role for TNF-induced apoptosis in vivo. Here, we describe a novel role for TNF in prostate epithelial cell apoptosis after androgen withdrawal. Emplo...

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Bibliographic Details
Main Authors: Davis, Jennifer S., Nastiuk, Kent L., Krolewski, John J.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386546/
https://ncbi.nlm.nih.gov/pubmed/21292828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0312
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