Progesterone Receptor Directly Inhibits β-Casein Gene Transcription in Mammary Epithelial Cells Through Promoting Promoter and Enhancer Repressive Chromatin Modifications

Differentiated HC-11 cells ectopically expressing progesterone receptor (PR) were used to explore the molecular mechanisms by which progesterone suppresses β-casein gene transcription induced by prolactin (PRL) and glucocorticoids in the mammary gland. As detected by chromatin immunoprecipitation as...

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Detalhes bibliográficos
Main Authors: Buser, Adam C., Obr, Alison E., Kabotyanski, Elena B., Grimm, Sandra L., Rosen, Jeffrey M., Edwards, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386529/
https://ncbi.nlm.nih.gov/pubmed/21527503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-0064
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