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Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90

Sulforaphane [1-isothiocyanato-4-(methyl-sulfinyl) butane)], an isothiocyanate derived from cruciferous vegetables, has been shown to possess potent chemopreventive activity. We analyzed the effect of sulforaphane on the proliferation of pancreatic cancer cells. Sulforaphane inhibited pancreatic can...

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Библиографические подробности
Главные авторы: Li, Yanyan, Karagöz, G. Elif, Seo, Young Ho, Zhang, Tao, Jiang, Yiqun, Yu, Yanke, Duarte, Afonso M.S., Schwartz, Steven J., Boelens, Rolf, Carroll, Kate, Rüdiger, Stefan G. D., Sun, Duxin
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386376/
https://ncbi.nlm.nih.gov/pubmed/22444872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2011.11.004
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