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The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration

Cell migration is essential for various physiological and pathological processes. Polarization in motile cells requires the coordination of several key signaling molecules, including RhoA small GTPases and phosphoinositides. Although RhoA participates in a front–rear polarization in migrating cells,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kato, Katsuhiro, Yazawa, Tsubasa, Taki, Kentaro, Mori, Kazutaka, Wang, Shujie, Nishioka, Tomoki, Hamaguchi, Tomonari, Itoh, Toshiki, Takenawa, Tadaomi, Kataoka, Chikako, Matsuura, Yoshiharu, Amano, Mutsuki, Murohara, Toyoaki, Kaibuchi, Kozo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386222/
https://ncbi.nlm.nih.gov/pubmed/22593208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0958
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