A Proteomic Approach for Comprehensively Screening Substrates of Protein Kinases Such as Rho-Kinase

BACKGROUND: Protein kinases are major components of signal transduction pathways in multiple cellular processes. Kinases directly interact with and phosphorylate downstream substrates, thus modulating their functions. Despite the importance of identifying substrates in order to more fully understand...

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Detalhes bibliográficos
Main Authors: Amano, Mutsuki, Tsumura, Yuta, Taki, Kentaro, Harada, Hidenori, Mori, Kazutaka, Nishioka, Tomoki, Kato, Katsuhiro, Suzuki, Takeshi, Nishioka, Yosuke, Iwamatsu, Akihiro, Kaibuchi, Kozo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806833/
https://ncbi.nlm.nih.gov/pubmed/20090853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008704
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