A Proteomic Approach for Comprehensively Screening Substrates of Protein Kinases Such as Rho-Kinase

BACKGROUND: Protein kinases are major components of signal transduction pathways in multiple cellular processes. Kinases directly interact with and phosphorylate downstream substrates, thus modulating their functions. Despite the importance of identifying substrates in order to more fully understand...

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Autors principals: Amano, Mutsuki, Tsumura, Yuta, Taki, Kentaro, Harada, Hidenori, Mori, Kazutaka, Nishioka, Tomoki, Kato, Katsuhiro, Suzuki, Takeshi, Nishioka, Yosuke, Iwamatsu, Akihiro, Kaibuchi, Kozo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806833/
https://ncbi.nlm.nih.gov/pubmed/20090853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008704
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