A Proteomic Approach for Comprehensively Screening Substrates of Protein Kinases Such as Rho-Kinase

BACKGROUND: Protein kinases are major components of signal transduction pathways in multiple cellular processes. Kinases directly interact with and phosphorylate downstream substrates, thus modulating their functions. Despite the importance of identifying substrates in order to more fully understand...

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Main Authors: Amano, Mutsuki, Tsumura, Yuta, Taki, Kentaro, Harada, Hidenori, Mori, Kazutaka, Nishioka, Tomoki, Kato, Katsuhiro, Suzuki, Takeshi, Nishioka, Yosuke, Iwamatsu, Akihiro, Kaibuchi, Kozo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806833/
https://ncbi.nlm.nih.gov/pubmed/20090853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008704
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