New Insights into Fluoroquinolone Resistance in Mycobacterium tuberculosis: Functional Genetic Analysis of gyrA and gyrB Mutations

Fluoroquinolone antibiotics are among the most potent second-line drugs used for treatment of multidrug-resistant tuberculosis (MDR TB), and resistance to this class of antibiotics is one criterion for defining extensively drug resistant tuberculosis (XDR TB). Fluoroquinolone resistance in Mycobacte...

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Autors principals: Malik, Seidu, Willby, Melisa, Sikes, David, Tsodikov, Oleg V., Posey, James E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386181/
https://ncbi.nlm.nih.gov/pubmed/22761889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039754
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