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Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations

Combinatorial gene perturbations provide rich information for a systematic exploration of genetic interactions. Despite successful applications to bacteria and yeast, the scalability of this approach remains a major challenge for higher organisms such as humans. Here, we report a novel experimental...

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Detalhes bibliográficos
Main Authors: Wang, Xin, Castro, Mauro A., Mulder, Klaas W., Markowetz, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386165/
https://ncbi.nlm.nih.gov/pubmed/22761558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002566
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