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Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition
The bacterial Sm-like protein Hfq is a central player in the control of bacterial gene expression. Hfq forms complexes with small regulatory RNAs (sRNAs) that use complementary “seed” sequences to target specific mRNAs. Hfq forms hexameric rings, which preferably bind uridine-rich RNA 3′ ends on the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386104/ https://ncbi.nlm.nih.gov/pubmed/22645344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202521109 |
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