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Accurate de novo structure prediction of large transmembrane protein domains using fragment-assembly and correlated mutation analysis

A new de novo protein structure prediction method for transmembrane proteins (FILM3) is described that is able to accurately predict the structures of large membrane proteins domains using an ensemble of two secondary structure prediction methods to guide fragment selection in combination with a sco...

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Detalhes bibliográficos
Main Authors: Nugent, Timothy, Jones, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386101/
https://ncbi.nlm.nih.gov/pubmed/22645369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120036109
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