Identification of the platelet-derived chemokine CXCL4/PF-4 as a broad-spectrum HIV-1 inhibitor

The natural history of HIV-1 infection is highly variable in different individuals, spanning from a rapidly progressive course to a long-term asymptomatic infection. A major determinant of the pace of disease progression is the in vivo level of HIV-1 replication, which is regulated by a complex netw...

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Bibliographic Details
Main Authors: Auerbach, David J., Lin, Yin, Miao, Huiyi, Cimbro, Raffaello, DiFiore, Michelle J., Gianolini, Monica E., Furci, Lucinda, Biswas, Priscilla, Fauci, Anthony S., Lusso, Paolo
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386099/
https://ncbi.nlm.nih.gov/pubmed/22645343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207314109
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