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HLA-C and HIV-1: friends or foes?

The major histocompatibility complex class I protein HLA-C plays a crucial role as a molecule capable of sending inhibitory signals to both natural killer (NK) cells and cytotoxic T lymphocytes (CTL) via binding to killer cell Ig-like receptors (KIR). Recently HLA-C has been recognized as a key mole...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zipeto, Donato, Beretta, Alberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386009/
https://ncbi.nlm.nih.gov/pubmed/22571741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-39
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