HLA-C increases HIV-1 infectivity and is associated with gp120

BACKGROUND: A recently identified genetic polymorphism located in the 5' region of the HLA-C gene is associated with individual variations in HIV-1 viral load and with differences in HLA-C expression levels. HLA-C has the potential to restrict HIV-1 by presenting epitopes to cytotoxic T cells b...

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Bibliografiske detaljer
Main Authors: Matucci, Andrea, Rossolillo, Paola, Baroni, Miriam, Siccardi, Antonio G, Beretta, Alberto, Zipeto, Donato
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531131/
https://ncbi.nlm.nih.gov/pubmed/18673537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-68
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