Vasoconstriction Potency Induced by Aminoamide Local Anesthetics Correlates with Lipid Solubility

Aminoamide local anesthetics induce vasoconstriction in vivo and in vitro. The goals of this in vitro study were to investigate the potency of local anesthetic-induced vasoconstriction and to identify the physicochemical property (octanol/buffer partition coefficient, pKa, molecular weight, or poten...

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Détails bibliographiques
Auteurs principaux: Sung, Hui-Jin, Ok, Seong-Ho, Sohn, Jin-Young, Son, Yong Hyeok, Kim, Jun Kyu, Lee, Soo Hee, Han, Jeong Yeol, Lim, Dong Hoon, Shin, Il-Woo, Lee, Heon-Keun, Chung, Young-Kyun, Choi, Mun-Jeoung, Sohn, Ju-Tae
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385964/
https://ncbi.nlm.nih.gov/pubmed/22778542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/170958
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