Vasoconstriction Potency Induced by Aminoamide Local Anesthetics Correlates with Lipid Solubility

Aminoamide local anesthetics induce vasoconstriction in vivo and in vitro. The goals of this in vitro study were to investigate the potency of local anesthetic-induced vasoconstriction and to identify the physicochemical property (octanol/buffer partition coefficient, pKa, molecular weight, or poten...

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書誌詳細
主要な著者: Sung, Hui-Jin, Ok, Seong-Ho, Sohn, Jin-Young, Son, Yong Hyeok, Kim, Jun Kyu, Lee, Soo Hee, Han, Jeong Yeol, Lim, Dong Hoon, Shin, Il-Woo, Lee, Heon-Keun, Chung, Young-Kyun, Choi, Mun-Jeoung, Sohn, Ju-Tae
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385964/
https://ncbi.nlm.nih.gov/pubmed/22778542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/170958
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