Vasoconstriction Potency Induced by Aminoamide Local Anesthetics Correlates with Lipid Solubility

Aminoamide local anesthetics induce vasoconstriction in vivo and in vitro. The goals of this in vitro study were to investigate the potency of local anesthetic-induced vasoconstriction and to identify the physicochemical property (octanol/buffer partition coefficient, pKa, molecular weight, or poten...

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Главные авторы: Sung, Hui-Jin, Ok, Seong-Ho, Sohn, Jin-Young, Son, Yong Hyeok, Kim, Jun Kyu, Lee, Soo Hee, Han, Jeong Yeol, Lim, Dong Hoon, Shin, Il-Woo, Lee, Heon-Keun, Chung, Young-Kyun, Choi, Mun-Jeoung, Sohn, Ju-Tae
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385964/
https://ncbi.nlm.nih.gov/pubmed/22778542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/170958
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