Vasoconstriction Potency Induced by Aminoamide Local Anesthetics Correlates with Lipid Solubility

Aminoamide local anesthetics induce vasoconstriction in vivo and in vitro. The goals of this in vitro study were to investigate the potency of local anesthetic-induced vasoconstriction and to identify the physicochemical property (octanol/buffer partition coefficient, pKa, molecular weight, or poten...

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Detalhes bibliográficos
Main Authors: Sung, Hui-Jin, Ok, Seong-Ho, Sohn, Jin-Young, Son, Yong Hyeok, Kim, Jun Kyu, Lee, Soo Hee, Han, Jeong Yeol, Lim, Dong Hoon, Shin, Il-Woo, Lee, Heon-Keun, Chung, Young-Kyun, Choi, Mun-Jeoung, Sohn, Ju-Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385964/
https://ncbi.nlm.nih.gov/pubmed/22778542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/170958
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