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Fibroblast progenitor cells are recruited into the myocardium prior to the development of myocardial fibrosis

Using an established model of myocardial hypertrophy and fibrosis after angiotensin II (AngII) infusion, our aim was to characterize the early cellular element involved in the development of myocardial fibrosis in detail. Male Lewis rats were infused with saline or AngII (0.7 mg/kg per day) for up t...

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Autors principals: Sopel, Mryanda, Falkenham, Alec, Oxner, Adam, Ma, Irene, Lee, Timothy DG, Légaré, Jean-Francois
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385703/
https://ncbi.nlm.nih.gov/pubmed/22225615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2011.00797.x
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