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Deregulation of the CXCL12/CXCR4 axis in methotrexate chemotherapy–induced damage and recovery of the bone marrow microenvironment

Cancer chemotherapy disrupts the bone marrow (BM) microenvironment affecting steady-state proliferation, differentiation and maintenance of haematopoietic (HSC) and stromal stem and progenitor cells; yet the underlying mechanisms and recovery potential of chemotherapy-induced myelosuppression and bo...

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Autors principals: Georgiou, Kristen R, Scherer, Michaela A, King, Tristan J, Foster, Bruce K, Xian, Cory J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385702/
https://ncbi.nlm.nih.gov/pubmed/22220905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2011.00800.x
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