Gefitinib Radiosensitizes Non–Small Cell Lung Cancer Cells by Suppressing Cellular DNA Repair Capacity

PURPOSE: Overexpression of the epidermal growth factor receptor (EGFR) promotes unregulated growth, inhibits apoptosis, and likely contributes to clinical radiation resistance of non – small cell lung cancer (NSCLC). Molecular blockade of EGFR signaling is an attractive therapeutic strategy for enha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tanaka, Toshimitsu, Munshi, Anupama, Brooks, Colin, Liu, Jenny, Hobbs, Marvette L., Meyn, Raymond E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385646/
https://ncbi.nlm.nih.gov/pubmed/18281562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1606
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